Lymphogranuloma venereum

LGV is caused by L1, L2, and L3 serovars of Chlamydia trachomatis and is more common in 20-30 year olds, multiple sexual partners, other SAIs and social deprivation.  Initial manifestation is an ulcer.  This is followed by painful enlargement of the lymph nodes in the groin region.  The third stage is that of a rupture through the skin and purulent discharge. Finally it may lead to stricture of rectum and vagina.

It is typically treated with a longer period of antibiotics such as Deoxycycline or Azithromycin. Aspiration, incision and drainage might be required to remove buboes and prevent further ulcerations forming. Typically there may be a secondary bacterial infection therefore this too needs to be treated.