HTLV

What is HLTV-1?
HTLV-1 is short for Human T-Cell Lymphotropic Virus Type 1. It is a lifelong infection and is generally asymptomatic for a number of years in most people infected with the virus, before symptoms start to show up. Unfortunately, it can lead to serious illnesses in some patients. In Malta, HTLV-1 is of concern among people coming from sub-Saharan Africa.

HTLV-1 is found in South America, the Caribbean, the southern part of Japan, Papua New Guinea.

How can I lower my risk for HTLV-1?

  • Use condoms every time you have sex.
  • Limit your number of partners.
  • Do not have sex if drunk or had used illicit drugs.
  • Do not share needles.


How does someone get HTLV-1?
It is transmitted through:

  • Unprotected sex.
  • Blood.
  • Sharing of needles with infected persons.
  • Vertical transmission: There is about 6-35% transmission from mother to infant through breast milk. If you are breastfeeding, you either avoid breastfeeding, or limit breastfeeding for not more than 6 months. It is important to discuss this with your medical practitioner or midwife.

You cannot get HTLV-1 by hugging, kissing or sharing a glass.

What are the symptoms of HTLV-1?
Slow onset of disease, which generally takes 20-30 years (unlike HIV which takes 5-10 years) before symptoms start to show up. Many do not show any symptoms at all. About 5% of those infected develop one of the following serious illnesses:

  • Adult T-cell leukemia/lymphoma:
    • Fatigue.
    • Swollen lymph nodes.
    • Fever with sweats.
    • Skin rash.
    • Bone lesions.
    • Aggressive Malignancy.
  • Tropical Spastic Paraparesis (mainly seen in the Caribbean) and HTLV Associated Myelopathy (mainly seen in Japan):
    • Muscle stiffness.
    • Muscle spasms.
    • Stiff gait.
    • Weakness in lower extremity of the body.
    • Low back pain.
    • Unable to control urinary bladder and/or bowels.
    • Impotence.
    • Tingling sensation/numbness.
    • Over active reflexes.
  • Infective Dermatitis:
    • Recurrent Staphylococcus or Streptococcus skin infections.
  • Uveitis:
    • Sudden onset, reddening of eyes, pain and blurred vision.
  • Polymyositis:
    • Muscle pain.
    • Muscle stiffness.
    • Muscle weakness mainly in abdomen, shoulders and upper arms, hips.
    • Joint pain.
    • Joint stiffness.
    • Irregular heart beats.
    • Difficulty breathing.
    • Difficulty swallowing.


How can I find out if I have HTLV-1?
The doctor may carry out a blood test. You may get tested for other STIs as one can have other sexually transmitted infections at the same time.

When should I be tested?

  • If you had or are having unprotected vaginal, anal or oral sex.
  • If you are having unprotected sex with more than one partner.
  • You may get to know that you have the infection while you are being tested for other reasons, in view that many do not have any symptoms.


Do I have to inform my partner about HTLV-1?

  • Your partner may have HTLV-1 too.
  • Be sure to tell your recent sex partner/s so that they can get tested and treated. They may have it too without knowing it.
  • Healthcare professionals may help you in notifying your sexual partners in a confidential manner.


How is HLTV-1 treated?
HTLV-1 is a lifelong infection and there is no specific treatment for it. Treatment is given according to your symptoms and/or signs and it may include antivirals, chemotherapy or other treatment. You should discuss with your doctor.

Further information and help

  • Talk to your doctor.
  • Call the GU Clinic on 25457494/1 for an appointment.


Reference List:

https://www.healthdirect.gov.au/htlv-1-infection

ncbi.nlm.nih.gov/pmc/articles/PMC2901658/